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6 However, oxymorphone has a significantly longer half life (7-9 hours)7 than does oxycodone, whose mean elimination half-life following a single, buprenorphine oral dose is 3 . 43 buprenorphine hours . buprenorphine Oxycodone is metabolized in part by cytochrome P450 2D6 to oxymorphone, which represents less than 15% of the total administered dose . 51 buprenorphine quantitative buprenorphine equianalgesic dosing buprenorphine kratom buprenorphine � 1 .
Oxymorphone (brand names Opana, Numorphan, Numorphone), also known as 14-hydroxydihydromorphinone, is a powerful buprenorphine semi-synthetic opioid analgesic (painkiller) first developed in Germany in 1914, patented in the USA by Endo Pharmaceuticals in 1955 and introduced to the United States market in January 1959 and other .

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