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Get alesse emergency medical help if you have any of these signs of an allergic reaction to Alesse: hives; difficult breathing; swelling of your face, lips, tongue, or throat .
Early investigations of high dose estrogen combinations (50 mcg or more of alesse ethinyl estradiol or equivalent daily) suggested that women may be at increased risk of cardiovascular complications (myocardial infarction, stroke, and vascular thrombosis, including venous thromboembolism) . More recent investigations of low dose estrogen combinations have suggested that alesse oral contraceptive use is not associated with an increased risk of serious cardiovascular complications in healthy non smoking women up to the age of 45 . Oral contraceptive use for women aged 35 to 44 who smoke or who have preexisting systemic diseases alesse that may affect the cardiovascular system is not recommended .
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