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The remeron mechanism of action of REMERON (mirtazapine) Tablets, as with other drugs effective in the treatment of major depressive disorder, is unknown .
Following oral administration remeron of REMERON (mirtazapine) Tablets 20 mg/day for 7 days to subjects of varying ages (range, 25 - 74), oral clearance of mirtazapine was reduced in the elderly compared to the younger subjects . The differences were most striking in males, with a 40% lower clearance in elderly males compared to younger males, while the clearance remeron in elderly females was only 10% lower compared to younger females . Caution is indicated in remeron administering REMERON to elderly patients (see PRECAUTIONS and DOSAGE AND ADMINISTRATION) .

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